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Doloprin

(Enteric-Coated Aspirin for Prevention of Heart Attack)

Doloprin® is an effective blood-thinner that assures uninterrupted blood circulation. It protects your heart and reduces risk of cardiac arrest and sudden death. We have made it enteric-coated to suit all patients, particularly those at risk of gastrointestinal ulcers. The drug is recommended for primary and secondary prevention of heart disease.

Active Ingredients

Aspirin

Role: Aspirin stops clots formation in the blood vessels and ensures uninterrupted blood flow throughout the body. The clots partially or completely block the blood vessels thereby hampering blood flow and increasing stress on the heart. As a result the blood flow and oxygen supply to different parts of the body is restricted (ischemia). When the clot is bigger, it completely occludes blood flow increasing risk of a sudden heart attack.

Aspirin prevents all of this. It is a platelet-aggregation inhibitor and prevents clot formation. It also breaks down existing clots.

Aspirin also resolves inflammation and fever.

Mechanism of Action

 

Doloprin® Tablets work by dual mechanisms:

  • First, it inhibits COX-1 & COX-2 receptors necessary for mediating inflammatory activity, pain and body temperature.

  • Second, it blocks the Thromboxane-A2 enzyme which is essential for platelets aggregation during clotting activity.

Contraindications

You should not or use only after consultation with the doctor or the pharmacist if you have any of the following conditions:

  • Aspirin allergy

  • Pregnancy or breastfeeding

  • Gastric ulcers

  • Reye’s syndrome, a disease causing swelling in the brain and liver

  • Heavy menstrual bleeding

Uses

  • Inflammation

  • Rheumatic fever

  • Pain or cramps

  • Angina

  • Obese patients

  • Myocardial Infarction

  • After operation drug to prevent clots

Doloprin is used for primary prevention of cardiac arrest in:

  • Men over 40
  • Smokers
  • Medical conditions that inadvertently stress heart such as diabetes, hypertension and hyperlipidemia
  • Postmenopausal women
  • Adults with sedentary lifestyle
  • Stress
  • History of cardiovascular disease

Doloprin is prescribed for secondary prevention of cardiac arrest in:

  • Non-fatal myocardial infarction (MI)
  • Acute MI
  • Transient ischemic attack (TIA)
  • Unstable angina
  • Stroke
  • Thromboembolic disorders

Doloprin® is also safe to use after coronary artery bypass graft surgery (CABG). In fact, the use of drug reduces risk of ischemia and death after the surgery.

 

Drug Interactions

Avoid the following medicines or consult your doctor prior to using Doloprin

  • Non-Steroidal Anti-inflammatory Drugs

  • Anticoagulants

  • Renin-angiotensin Inhibitors

  • Anit-gout drugs

  • Methotrexate

  • Anti-seizure drugs

  • Hypoglycemics

  • Citrates

Precautions

Prior to using Doloprin® Tablets, please inform your doctor about:

  • Your medical history, allergies, and medicines you take at present

  • Pregnancy or lactation

Dosage & Instructions

Doloprin® tablets are prescribed by the doctor according to the patient’s condition.

The usual dose is 1 to 2 tablets twice a day.

Side Effects

Common side effects are:

  • Nausea, vomiting or diarrhea

  • Indigestion

  • Drowsiness

Stop your medicine and inform your doctor if you notice:

  • Allergic reaction or skin rash forms

  • Respiratory problems

  • Bloody diarrhea or vomiting

  • Severe pain

  • Palpitations or increased heart rate

  • Any other severe problem