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Fantar DS

(Artemether & Lumefantrine)

Fantar® DS and Fantar® Forte are a potent duo of two anti-malarials drugs, i.e., Artemether and Lumefantarine. Together, these drugs cure malaria within three days. You will see sign of improvement in first 8 hours of drug intake.

Malaria is caused by the bite of female virus-carrier mosquito. It affects the large majority of local population. In 2011, 4.3 million Pakistanis succumbed to malaria while 26 million are at a risk of developing the infection. Fantar is effective against both species of malaria causing viruses, i.e., P.falciparum and P.vivax.

Active Ingredients & Mechanism of Action

  • Artemether – It kills the malaria-causing parasite known as Plasmodium and its species.
  • Lumefantrine – It is also an anti-malarial drug effective against Plasmodium in its erythrocytic stage.

Fantar® kills the plasmodium by inhibiting nucleic acid and protein formation processes and preventing the growth of malarial parasites in the blood.

 

Uses

Acute & uncomplicated malaria

Contraindications

 

  • Hypersensitivity to antimalarials

  • Cardiac problems

  • Complicated malaria

  • Long QT syndrome patients

  • Disturbed body electrolytes

Drug Interactions

Avoid the following medicines or consult your doctor prior to using Fantar® Tablets:

  • Hormonal contraceptives

  • Anti Retroviral therapy drugs

  • Mefloquine

  • Anti-fungals

  • Medicines which are degraded by the CYP2D6 enzyme

  • Anti-arrhythmic drugs

Dosage & Instructions

Fantar® 3-day regimen is:

  • Patients between 15-35kg 1st day: 1 tablet in the morning then second tablet after 8 hours

2nd & 3rd day: 1 tablet in the morning then second tablet in the evening

  • Above 35kg 1st day: 2 tablets in the morning then 2 tablets after 8 hours

2nd & 3rd day: 2 tablets in the morning then 2 tablets in the evening

Precautions

Before using Fantar®, please inform your doctor about:

  • Your medical history, allergies, and medicines you take at present

  • Pregnancy or lactation

Side Effects

Common side effects are:

  • Nausea, vomiting diarrhea

  • Fatigue

  • Sleeplessness

  • Dizziness & headache

Stop this medicine and consult your doctor if:

  • Allergic rashes

  • Severe pain

  • Fainting & palpitations

  • Breathing discomfort

  • Nervous system or cardiac problem

  • Any other severe condition