Pakistan's First and only MHRA Certified Company

Napreben 275mg

(Naproxen Betaine Sodium)

The Magical Elixir you need for quick pain relief

Napreben® is our trademark product and one of the best pain-relief formulations developed to date. It acts quickly, provides relief within 15 minutes of application or ingestion and is at least 20 times faster than aspirin and ibuprofen. It has a great tolerability profile and is practically safe in children, adults and elderly.

We formulate Napreben® is two dosage forms, i.e., capsules and topical gel form for ease of use and better patient compliance.

Active Ingredients & Mechanism of Action

Naproxen Sodium: is a potent inhibitor of prostaglandin synthesis, a chemical responsible for pain, inflammation and fever. Naproxen exerts its anti-inflammatory, anti-pyretic and analgesic effect by inhibiting cyclooxegenase (COX-1 & COX-II) enzymes that catalyze formation of prostaglandins.

Betaine: assists in the rapid absorption of naproxen sodium into the stomach mucosa to relieve pain rapidly. It also reduces acid production in the stomach and reduces risk of gastrointestinal (GI) ulceration.

Why Napreben® & not Other Ordinary Pain Killers?

Napreben® is a powerful pain reliever that far surpasses aspirin and ibuprofen – the quintessential analgesics and anti-inflammatory. In fact, what makes Napreben® superior is that it has the lowest rate and tendency to cause GI complications. Napreben®  is cosmetically acceptable to the patient because of ease of use. The drug is absorbed quickly from the skin/gastrointestinal tract and reaches site of action to exert potent effect that stays round the clock (24 hours). It is 100% efficient and well-tolerated. Most importantly, it is economical.


  • Acute pain or inflammation of muscles, tendons, ligaments & vertebrae

  • Fever

  • Menstrual cramps

  • Headache

  • Swollen joints

  • Neuralgia

  • Acute migraine attack

  • Orthopedic rehabilitation therapy

  • Post-surgical joint and muscular pain

Drug Interactions

Avoid the following medicines or consult your doctor prior to using Napreben® Tablets:

  • Aspirin

  • Growth hormone medications

  • Anticoagulants

  • Anti-acids

  • Tissue transplant drugs

  • Gout medicines

  • Corticosteroids

  • Diuretics


  • Peptic ulcers

  • Blood disorders

  • Imbalanced body electrolytes

  • Pregnancy & lactation

Side Effects

Common side effects observed are:

  • Nausea, vomiting or diarrhea

  • Headache, dizziness or drowsiness

Halt your medication & consult your doctor if:

  • Allergic skin rashes

  • Too high or low blood pressure

  • Confusion, palpitations or any nervous system disorder

  • Bloody diarrhea

  • Respiratory problem

  • Severe pain

  • Edema

  • Blurred vision

Dosage & Instructions

  • Capsules:2-3 capsules per day with meals

  • Gel: Three times daily


Prior to using Napreben®, please inform your doctor about:

  • Your medical history, allergies, and medicines you take at present

  • Pregnancy or lactation