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Rifin Forte

(Rifampicin, Isoniazid, Pyrazinamide & Ethambutol-HCl)

Rifin Forte® is a WHO-recommended treatment for tuberculosis. It based on the tetra-antibiotic formulation that provides reliable results and patient compliance.

How Rifin Forte Works in Your Body

· Rifampicin

Mechanism:  It kills bacteria by arresting protein synthesis and hence, its growth.

· Isoniazid

Mechanism: It stops cell wall synthesis in mycobacteria thereby preventing the bacterial growth.

· Pyrazinamide

Mechanism: It disrupts mycobacterial bacilli cell membrane making it more acidic and prone to disruption.

· Ethambutol Hydrochloride

Mechanism: It disrupts cell wall synthesis and stops bacterial growth.

Indications

  • Tuberculosis
  • Meningitis
  • Spinal cord bacterial infection
  • Severe diseases of skin, nerves and mucous membranes

Contraindications

  • Allergy to any of its ingredients
  • Pregnancy & breastfeeding
  • Gout
  • Bleeding disorders

Drug Interactions

Rifin Forte® has a propensity to interact with other drugs. Avoid the following medicines or consult your doctor prior to taking Rifin® Forte:

  • Anesthetics like halothane
  • Citalopram
  • Imatinib
  • Enalapril
  • Eplerenone

Dosage & Instructions

Consult your doctor for dosage. Usually, it is:

  • New Tb cases Initial phase 3 months treatment:
  • 30-39kg 2 tablets daily
  • 40-54kg 3 tablets daily
  • 55-79kg 4 tablets daily
  • Recurrent Tb Cases Initial phase treatment for Recurrent TB cases is:

Take Rifin® Forte with Streptomycin for 2 months then for the next 1 month take Rifin® Forte alone.

 

Side Effects

  • Nausea
  • Loss of appetite
  • Diarrhea
  • Headache
  • Fatigue

Leave Rifin® Forte and see a doctor immediately if you notice any of the follow symptoms:

  • Allergic skin rashes
  • Severe pain
  • Toxic psychosis
  • High blood pressure or sugar level
  • Cardiac or respiratory problem

Precautions

Before using Rifin Forte®, inform your doctor about:

  • Medications you are taking
  • History of allergy or any other present health condition
  • Pregnancy or lactation