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Valvozid 5

(Bisoprolol Fumarate)

Valvozid® is a combination drug that reduces risk of sudden death in hypertensive and cardiac patients. Its efficacy far surpasses other traditional treatments in successfully managing angina, congestive heart failure and hypertension. With Valvozid, the risk of following complications reduces markedly:

  • All-cause mortality – 34%
  • Sudden death – 44%
  • All-cause hospitalization – 20%
  • Hospitalization due to worsening heart failure – 36%

Active Ingredients

Bisoprolol Fumarate reduces stress on the heart by decreasing heart rate and blood pressure.

Hydrochlorothiazide is a diuretic that helps in balancing of bodily fluid electrolytes.

Mechanism of Action

Valvozid® blocks β1 adrenergic receptors which are responsible for increasing heart contractility, heart rate, and blood pressure.

Valvozid®-5 Plus has an additional property of balancing body fluid electrolytes by acting on catecholamine proximal tubules of the kidney


  • High blood pressure
  • Chronic heart failure or stroke
  • Angina
  • Edema or fluid retention
  • Kidney electrolytes imbalance
  • Cardiac arrhythmia
  • Tachycardia


  • Allergic to its ingredients
  • Bradycardia
  • Pregnancy or breastfeeding
  • Asthma
  • 2nd or 3rd degree Heart block
  • Hyperlipidemia

Drug Interactions

Avoid the following medicines or consult your doctor prior to taking Valvozid® Tablets as it may disturb the efficacy and function of the drug:

  • Aspirin
  • Corticosteroids
  • Alcohol
  • Digitalis
  • Alcohol
  • Cholestyramine

Dosage & Instructions

Dosage is as per your doctor’s recommendation. Usually, its dose is:

  • 1-2 tablets two times daily for Valvozid® 5mg
  • 1-2 tablets once daily for Valvozid® 10mg


Prior to taking Valvozid® Tablets, please inform your doctor about:

  • Your medical history, allergies, and medicines you take at present
  • Pregnancy or lactation

Side Effects

Usual side effects are:

  • Nausea, vomiting or diarrhea
  • Headache
  • Dizziness
  • Indigestion
  • fatigue

Discontinue and see your doctor if:

  • Allergic reaction
  • Severe pain
  • Fainting
  • Difficulty in breathing
  • Slow heartbeat
  • Nervousness
  • Any other severe condition